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4- Biochemistry 4 (1 Hour & 52 minutes)

[vdo id=’a36bc91a09004a34b014c36bf2b0f668′]

 

   Content of this Session
  • tRNA
  • Genetic code features
  • Protein Translation
  • Posttranslational modifications
  • Chaperone protein
  • Proteasomes and Ubiquitin

 

 

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[h] Biochemistry Flashcards

[i] Master this session in just 5 minutes.

[q] …….. contains the TΨC (ribothymidine, pseudouridine, cytidine) sequence necessary for tRNA-ribosome binding.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFQtYXJtLiBULWFybSBUZXRoZXJzIHRSTkEgbW9sZWN1bGUgdG8gcmlib3NvbWUu

Cg==

Cg==[Qq]

[q] ……. contains dihydrouridine residues necessary for tRNA recognition by the correct aminoacyl-tRNA synthetase.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEQtYXJtLiBELWFybSBEZXRlY3RzIHRoZSB0Uk5BIGJ5IGFtaW5vYWN5bC10Uk5BIHN5bnRoZXRhc2Uu

Cg==

Cg==[Qq]

[q] ………. is located on the opposite end of the tRNA molecule. It recognizes and binds the mRNA codon and assures placement of the proper amino acid in the growing polypeptide chain.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFRoZSBhbnRpY29kb24u

Cg==

Cg==[Qq]

[q] Amino acid activation and attachment to the 3′ end of tRNA is catalyzed by ………..?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IGFtaW5vYWN5bC10Uk5BIHN5bnRoZXRhc2VzIChBQS10Uk5BIHN5bnRoZXRhc2VzLCB1c2VzIEFUUCku

Cg==

Cg==[Qq]

[q] tRNA that is mischarged with the incorrect amino acid (and not corrected by AA-tRNA synthetase proofreading) will incorporate ………. into the growing polypeptide chain

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IHRoZSB3cm9uZyBhbWlubyBhY2lkLiBUaGVyZSBpcyBubyBhbWlubyBhY2lkIHByb29mcmVhZGluZyBkdXJpbmcgcHJvdGVpbiB0cmFuc2xhdGlvbi4=[Qq]

[q] Because of the degeneracy of the code, certain tRNA molecules can recognize multiple different codons coding for the same amino acid, a phenomenon explained by the ………….?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]ICYjODIyMDt3b2JibGUmIzgyMjE7IGh5cG90aGVzaXMu

Cg==

Cg==[Qq]

[q] Translation occurs in the (cytoplasm or nucleus) of both prokaryotic (Pr) and eukaryotic (Eu) cells?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IGN5dG9wbGFzbS4=[Qq]

[q] In prokaryotes, the small subunit binds to ……….., but in eukaryotes, the small subunit binds to ………?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IHRoZSBTaGluZS1EYWxnYXJubyBzZXF1ZW5jZSBpbiB0aGUgNeKAsiB1bnRyYW5zbGF0ZWQgcmVnaW9uIG9mIHRoZSBtUk5BLCB0aGUgNeKAsiBjYXAgc3RydWN0dXJlLg==[Qq]

[q] Whenever protein synthesis occurs in a cell, a few copies of a particular protein may not fold correctly. These defective copies are covalently marked for destruction by the addition of ………?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IG11bHRpcGxlIGNvcGllcyBvZiB1YmlxdWl0aW4u

Cg==

Cg==[Qq]

[q] Defects in the ubiquitin-proteasome system have been implicated in some cases of ………?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFBhcmtpbnNvbiBhbmQgQWx6aGVpbWVy4oCZcyBkaXNlYXNlLg==

Cg==

Cg==[Qq]

[x][restart]

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