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Question 1 of 2
1. Question
A term newborn boy is evaluated in the neonatal intensive care unit for respiratory distress. Apgar scores are 2 and 5 at 1 and 5 minutes, respectively. Respirations are 84/min. On examination, the patient has a barrel chest with a scaphoid abdomen and mild cyanosis of his extremities. Auscultation shows absent breath sounds on the left; right lung aeration is normal. Chest x-ray reveals multiple fluid-containing cystic areas on the left and a mediastinal shift to the right. Which of the following embryologic events most likely failed to occur in this patient?
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Question 2 of 2
2. Question
A 62-year-old man comes to the office for the evaluation of jaundice. Medical history is significant for uncontrolled type 2 diabetes mellitus and morbid obesity. He does not use tobacco, alcohol, or illicit drugs. There is no family history of liver disease. Vital signs are within normal limits. BMI is 47 kg/m2. Mild scleral icterus is present. Heart and lung sounds are normal. The abdomen is nontender and nondistended. Trace bilateral lower extremity edema is present. Laboratory studies reveal elevated transaminases. A liver biopsy is obtained, and trichrome staining shows the following:
Which of the following cells is directly responsible for the histologic finding indicated by the arrow?
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