[qwiz style=”width: auto !important; min-height: auto !important; border-width: 4px !important; border-color: #0099cc !important; ” align=”center”]

[h] Hematology & Oncology System Flashcards

[i] Master this session in just 5 minutes.

[q] What is the most likely diagnosis?

15 years old child presenting with epistaxis and Petechiae & Purpura + laboratory findings include: ↓ platelet count with prolonged bleeding time: often < 50,000 platelets per microliter (mcL), Normal PT/PTT, ↑ megakaryocytes on bone marrow biopsy. Symptoms respond well to corticosteroids.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEltbXVuZSB0aHJvbWJvY3l0b3BlbmljIHB1cnB1cmEgKElUUCkuIElUUCBpcyBjaGFyYWN0ZXJpemVkIGJ5IHRoZSBhdXRvaW1tdW5lIGRlc3RydWN0aW9uIG9mIHBsYXRlbGV0cyBieSBhbnRpLXBsYXRlbGV0IGFudGlib2RpZXMsIGxpa2VseSBJZ0cgYXV0b2FudGlib2RpZXMgYWdhaW5zdCB0aGUgcGxhdGVsZXQgbWVtYnJhbmUgZ2x5Y29wcm90ZWlucyBHUElJYi9sbGxhLg==[Qq]

[q] What is the most likely diagnosis?

10 years old child presenting with hematuria and Petechiae & Purpura, fever + Laboratory findings include: Thrombocytopenia with ↑ bleeding time, Normal PT/PTT, Anemia with schistocytes, ↑ Megakaryocytes on bone marrow biopsy, decreased hemoglobin and haptoglobin levels as well as increased serum lactate dehydrogenase and unconjugated bilirubin levels, elevated BUN and creatinine + the child has history of bloody diarrhea one week ago after eating undercooked beef.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEhlbW9seXRpYyB1cmVtaWMgc3luZHJvbWUgKEhVUykuIENsYXNzaWNhbGx5IHNlZW4gaW4gY2hpbGRyZW4gd2l0aCBFIGNvbGkgTzE1NzpINyBkeXNlbnRlcnksIHdoaWNoIHJlc3VsdHMgZnJvbSBleHBvc3VyZSB0byB1bmRlcmNvb2tlZCBiZWVmLiBFIGNvbGkgdmVyb3RveGluIGRhbWFnZXMgZW5kb3RoZWxpYWwgY2VsbHMgcmVzdWx0aW5nIGluIHBsYXRlbGV0IG1pY3JvdGhyb21iaS4=

[q] What is the most likely diagnosis?

30 years old MALE presenting with confusion, disorientation, hematuria and Petechiae & Purpura, fever + Laboratory findings include: Thrombocytopenia with ↑ bleeding time, Normal PT/PTT, Anemia with schistocytes, ↑ Megakaryocytes on bone marrow biopsy, decreased hemoglobin and haptoglobin levels as well as increased serum lactate dehydrogenase and unconjugated bilirubin levels.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFRocm9tYm90aWMgdGhyb21ib2N5dG9wZW5pYyBwdXJwdXJhIChUVFApLiBUVFAgaXMgZHVlIHRvIGRlY3JlYXNlZCBBREFNVFMxMyAodldGIG1ldGFsbG9wcm90ZWFzZSksIGFuIGVuenltZSB0aGF0IG5vcm1hbGx5IGNsZWF2ZXMgVndGIG11bHRpbWVycyBpbnRvIHNtYWxsZXIgbW9ub21lcnMuIExhcmdlLCB1bmNsZWF2ZWQgbXVsdGltZXJzIGxlYWQgdG8gYWJub3JtYWwgcGxhdGVsZXQgYWRoZXNpb24sIHJlc3VsdGluZyBpbiBtaWNyb3Rocm9tYmku

Jm5ic3A7

[Qq]

[q] …… is due to a genetic GP1b deficiency —> platelet adhesion is impaired, but …… is due to a genetic GIIb/llla deficiency —> platelet aggregation is impaired.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEJlcm5hcmQtU291bGllciBzeW5kcm9tZSwgR2xhbnptYW5uIHRocm9tYmFzdGhlbmlhLg==

[x][restart]

[/qwiz]