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[h] Microbiology & Antimicrobials Flashcards

[i] Master this session in just 5 minutes.

[q] Which type of proteolytic enzymes (Papain or pepsin) that can preserve the agglutination function of the antibody?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IHBlcHNpbi4gVGhlIGJyaWRnaW5nIG9mIGFudGlnZW5zIGJ5IGFudGlib2R5IG1vbGVjdWxlcyBpcyByZXF1aXJlZCBmb3IgYWdnbHV0aW5hdGlvbiBvZiBwYXJ0aWN1bGF0ZSBhbnRpZ2VucyBvciB0aGUgcHJlY2lwaXRhdGlvbiBvZiBzb2x1YmxlIGFudGlnZW5zLg==

Cg==

Cg==[Qq]

[q] The first isotype of immunoglobulin that can be produced by a B cell with or without T-cell help is ……..?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IElnTS4=[Qq]

[q] The IgM molecule on the surface of the B cell is a ………, but the secreted form of this molecule is a ………, held together in an extremely compact form by a J chain synthesized by the cell.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IG1vbm9tZXIsIHBlbnRhbWVyLg==

Cg==

Cg==[Qq]

[q] ……. activates complement, acts as an opsonin, and mediates ADCC. It is also actively transported across the placenta by receptor-mediated transport and thus plays a crucial role in protection of the fetus during gestation.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IElnRy4=

Cg==

Cg==[Qq]

[q] ……. is particularly important as a component of the colostrum, or the first breast milk fed to an infant after birth, where it functions to provide the infant with passive mucosal immunity.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IElnQS4=[Qq]

[q] ……. serves an important function in IgA transepithelial transport, and once in the lumen of the tract, has a function in protecting the molecule from proteolytic cleavage.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFRoZSBzZWNyZXRvcnkgY29tcG9uZW50Lg==

Cg==

[Qq]

[q] ……… is a complement product that enhance phagocytosis and also helps clear immune complexes.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEMzYi4=

Cg==

Cg==[Qq]

[q] ………….. are complement products that mediate anaphylaxis.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEMzYSwgQzRhLCBDNWEu

Cg==

Cg==[Qq]

[q] …….. is a complement product that act as a chemoattractant.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEM1YS4=

Cg==

Cg==[Qq]

[q] (Early or terminal) complement deficiencies increases risk of severe, recurrent pyogenic sinus and respiratory tract infections; susceptibility to type III hypersensitivity reactions.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEVhcmx5IGNvbXBsZW1lbnQgZGVmaWNpZW5jaWVzIChDMS1DNCku[Qq]

[q] (Early or terminal) complement deficiencies increases susceptibility to recurrent Neisseria bacteremia.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFRlcm1pbmFsIGNvbXBsZW1lbnQgZGVmaWNpZW5jaWVzIChDNS1DOSku[Qq]

[q] …………. causes complement-mediated lysis of RBCs and paroxysmal nocturnal hemoglobinuria.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IERBRiAoR1BJLWFuY2hvcmVkIGVuenltZSkgZGVmaWNpZW5jeS4=

Cg==

Cg==[Qq]

[q] ……… causes hereditary angioedema due to unregulated activation of kallikrein → ↑ bradykinin. Characterized by ↓ C4 levels. ACE inhibitors are contraindicated (also ↑ bradykinin). Symptoms include facial swelling (without urticaria), life-threatening laryngeal edema, and gastrointestinal manifestations (nausea/vomiting, colicky pain, diarrhea).

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEMxIGVzdGVyYXNlIGluaGliaXRvciBkZWZpY2llbmN5Lg==

Cg==

Cg==

[Qq]

[q] ……….. on both lgG and lgM is located in the Fc portion closer to the hinge region.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFRoZSBjb21wbGVtZW50IGJpbmRpbmcgc2l0ZS4=

Cg==

Cg==[Qq]

[q] Autosomal recessive deficiencies of the IFN-gamma receptor (or other elements of this pathway) result in ……….. in infancy or early childhood.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IGRpc3NlbWluYXRlZCBteWNvYmFjdGVyaWFsIGRpc2Vhc2Uu

Cg==

Cg==[Qq]

[q] Patients with IL-12 receptor deficiency suffer from severe mycobacterial infections due to the inability to mount a strong cell mediated granulomatous immune response. They are treated with ………..?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IElGTi15Lg==[Qq]

[q] The 2 mechanisms of killing by cytotoxic T lymphocytes induce the activation of ………. which activate the “death domain”.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IGNhc3Bhc2VzLg==

Cg==

Cg==[Qq]

[q] Atypical lymphocytes observed in the peripheral blood smears of patients with infectious mononucleosis represent ………?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IGFjdGl2YXRlZCBDRDgrIGN5dG90b3hpYyBULWx5bXBob2N5dGVzLg==

Cg==

Cg==[Qq]

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