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[h] Microbiology & Antimicrobials Flashcards

[i] Master this session in just 5 minutes.

[q] ……….. is obligate intracellular bacterium; cannot make ATP. Not seen on Gram stain because their cell wall lacks classic peptidoglycan (due to reduced muramic acid), rendering β-lactam antibiotics not effective in treatment.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IENobGFteWRpYSB0cmFjaG9tYXRpcy4=[Qq]

[q] Serotypes …………. of chlamydia trachomatis are the Leading cause of preventable infectious blindness in Africa.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFNlcm90eXBlcyBBLCBCLCBhbmQgQy4=[Qq]

[q] Serotypes …………. of chlamydia trachomatis cause disease characterized by an initial painless small ulcer on the genital mucosa. This ulcer is followed weeks later by swollen, painful inguinal nodes that coalesce, ulcerate, and rupture; these are referred to as buboes. Cytoplasmic inclusions seen on Giemsa or fluorescent antibody-stained smear?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFNlcm90eXBlcyBMMSwgMiwgMy4=[Qq]

[q] Serotypes …………. of chlamydia trachomatis cause neonatal conjunctivitis?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFNlcm90eXBlcyBEIHRocm91Z2ggSy4=[Qq]

[q] What is the most likely diagnosis?

22 years old patient presenting with headache, fever, maculopapular rash starts on ankles and wrists and then spreads to the trunk, palms, soles, and face (centripetal rash, from extremities to trunk)?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFJvY2t5IE1vdW50YWluIHNwb3R0ZWQgZmV2ZXIu

TWljcm9vcmdhbmlzbTogUmlja2V0dHNpYSByaWNrZXR0c2lpLCB2ZWN0b3I6IHRpY2sgKERlcm1hY2VudG9yKS4=

Rickettsii on the wRists, Typhus on the Trunk.

[q] What is the most likely diagnosis?

22 years old patient presenting with headache, fever, maculopapular rash that starts centrally and spreads out, sparing palms and soles?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFR5cGh1cy4=

RW5kZW1pYyAoZmxlYXMpOiBSLiB0eXBoaS4=

Epidemic (human body louse): R. prowazekii.

Rickettsii on the wRists, Typhus on the Trunk.

[q] What is the most likely diagnosis?

19 years old patient presenting with fever, chills, myalgia and headache + thrombocytopenia, leukopenia and elevated liver enzymes + mulberry-like inclusions in monocytes?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEVocmxpY2hpb3Npcy4=

[Qq]MEGA berry: Monocytes = Ehrlichiosis. Granulocytes = Anaplasmosis.

[q] What is the most likely diagnosis?

19 years old patient presenting with fever, chills, myalgia and headache + thrombocytopenia, leukopenia and elevated liver enzymes + mulberry-like inclusions in Granulocytes?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEFuYXBsYXNtb3Npcy4=

[Qq]MEGA berry: Monocytes = Ehrlichiosis. Granulocytes = Anaplasmosis.

[q] What is the most likely diagnosis?

19 years old farmer presenting with fever, chills, myalgia and retroorbital headache + thrombocytopenia, normal leukocyte count and elevated liver enzymes + symptoms of pneumonia?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFEgZmV2ZXIu

Q294aWVsbGEgYnVybmV0aWksIG5vIGFydGhyb3BvZCB2ZWN0b3Iu

Treatment: doxycycline (inhibitor of bacterial protein synthesis).

[q] ……….. is the smallest free-living (extracellular) bacteria, Resistant to the beta-lactam antibiotics (penicillin and cephalosporins), Unstainable by the Gram stain (but readily stained by Giemsa stain). They are the only bacteria that contain sterol in the cell membrane and require serum enriched medium containing cholesterol for in vitro culture (Eaton’s agar).

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IE15Y29wbGFzbWEu[Qq]

[q] What is the most likely diagnosis?

22 years old patient presenting with chronic dry nagging cough, low-grade fever, mild dyspnea + chest x-ray shows bilateral interstitial infiltrate + mild anemia + patient serum able to agglutinate RBCs in vitro at low temperatures?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFdhbGtpbmcgcG5ldW1vbmlhIGR1ZSB0byBpbmZlY3Rpb24gd2l0aCBNeWNvcGxhc21hIHBuZXVtb25pYWUu

RHJ1Z3MgdGhhdCBhcmUgZWZmZWN0aXZlIGFnYWluc3QgdGhlIE15Y29wbGFzbWEgZ2VudXMgaW5jbHVkZSBhbnRpLXJpYm9zb21hbCBhZ2VudHMgbGlrZSB0aGUgbWFjcm9saWRlcywgZG94eWN5Y2xpbmUsIG9yIGZsdW9yb3F1aW5vbG9uZS4=

[q] What is the most likely diagnosis?

21 years old patient presenting with Hypopigmented patches located on the back and chest that is more prominent in summer +  KOH mount of skin scales shows spaghetti and meatballs appearance on microscopy?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFBpdHlyaWFzaXMgb3IgdGluZWEgdmVyc2ljb2xvciBkdWUgdG8gaW5mZWN0aW9uIHdpdGggTWFsYXNzZXppYSBmdXJmdXIu[Qq]

[q] Tinea ………….. is the dermatophyte infection of the head and scalp. Associated with lymphadenopathy, alopecia, scaling.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IENhcGl0aXMu

[q] Tinea ……… occurs on body. Characterized by erythematous scaling rings (“ringworm”) and central clearing. Can be acquired from contact with an infected cat or dog.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IENvcnBvcmlzLg==

[q] Tinea ………… occurs in inguinal area. Often does not show the central clearing seen in tinea corporis.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IGNydXJpcy4=

[q] Tinea …….. is the ringworm of the bearded region.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IGJhcmJhZS4=

[q] Tinea ……… is a dermatophyte infection of the foot (athlete’s foot).

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IHBlZGlzLg==

[q] Tinea …….. occurs on nails (Onychomycosis).

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IHVuZ3VpdW0u

[q] What is the most likely diagnosis?

50 years old Gardner presenting with reddish nodule that later ulcerates along draining lymphatics appears at the site of  thorn prick + skin biopsy shows cigar shaped yeast?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFNwb3JvdHJpY2hvc2lzIGR1ZSB0byBpbmZlY3Rpb24gd2l0aMKgU3Bvcm90aHJpeCBzY2hlbmNraWku[Qq]

[q] What is the most likely diagnosis?

34 years old patient presenting with cough, fever, pleuritic chest pain and pulmonary infiltrates and cavitations in the upper lung lobes and calcified nodes and fibrotic scarring after cave exploration in Ohio + Examination of lung biopsy specimens and bone marrow aspirates shows oval or round yeasts within macrophage?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEhpc3RvcGxhc21hIGNhcHN1bGF0dW0gaW5mZWN0aW9uLg==

SW4gY2FzZSBvZiBkaXNzZW1pbmF0ZWQgaW5mZWN0aW9uICYjODIxMjsmZ3Q7IEJlY2F1c2UgdGhlIGZ1bmd1cyB0YXJnZXRzIGhpc3Rpb2N5dGVzIGFuZCB0aGUgcmV0aWN1bG9lbmRvdGhlbGlhbCBzeXN0ZW0g4oaSIGx5bXBoYWRlbm9wYXRoeSBhbmQgaGVwYXRvc3BsZW5vbWVnYWx5Lg==[Qq]

[q] What is the most likely diagnosis?

34 years old patient presenting with cough, fever, pleuritic chest pain and pulmonary infiltrates and cavitations in the upper lung lobes and calcified nodes and fibrotic scarring after recent travel to arizona + Examination of lung biopsy specimens shows thick-walled spherules packed with endospores?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IENvY2NpZGlvaWRlcyBJbW1pdGlzIGluZmVjdGlvbi4=

Q2FuIGRpc3NlbWluYXRlIHRvIGJvbmUgYW5kIHNraW4g4oaSIEFydGhyYWxnaWFzIChkZXNlcnQgcmhldW1hdGlzbSksIEVyeXRoZW1hIG5vZG9zdW0gKGRlc2VydCBidW1wcykgb3IgbXVsdGlmb3JtZS4=[Qq]

[q] What is the most likely diagnosis?

34 years old patient presenting with cough, fever, pleuritic chest pain and pulmonary infiltrates and cavitations in the upper lung lobes and calcified nodes and fibrotic scarring after recent travel to Mississippi + Examination of lung biopsy specimens shows round yeast with thick, doubly refractive walls “broad based budding”?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEJsYXN0b215Y2VzIGRlcm1hdGl0aWRpcy4=

SW4gaW1tdW5vY29tcHJvbWlzZWQgcGF0aWVudHMsIGJsYXN0b215Y29zaXMgY2FuIGNhdXNlIGRpc3NlbWluYXRlZCBkaXNlYXNlLiBQYXRpZW50cyBtYXkgZXhwZXJpZW5jZSBza2luIGxlc2lvbnMgKHZlcnJ1Y291cyBsZXNpb25zIGNhbiBzaW11bGF0ZSBTQ0MpLCBhbmQgYm9uZSBwYWluIChjYXVzZWQgYnkgbHl0aWMgbGVzaW9ucyku[Qq]

[q] What is the most likely diagnosis?

34 years old patient presenting with cough, fever, pleuritic chest pain and pulmonary infiltrates and cavitations in the upper lung lobes and calcified nodes and fibrotic scarring after recent travel to Great lakes + Examination of lung biopsy specimens shows captain’s wheel” formation?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFBhcmFjb2NjaWRpb2lkZXMgYnJhc2lsaWVuc2lzIGluZmVjdGlvbi4=[Qq]

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