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16- Microbiology 16 (3 Hours & 2 minutes)

[vdo id=’5ddcff2426ec4b3faaef8c1382d6512f’]

 

   Content of this Session
  • HSV-1 and HSV-2
  • Varicella Zoster Virus (HHV-3)
  • Epstein-Barr Virus (HHV-4)
  • Cytomegalovirus (HHV-5)
  • Human herpesviruses 6 and 7
  • HHV-8
  • Variola/Smallpox
  • Molluscum contagiosum
  • Norovirus
  • Hepeviridae
  • Enteroviruses
  • Rhinoviruses
  • Heparnaviruses

 

 

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[h] Microbiology & Antimicrobials Flashcards

[i] Master this session in just 5 minutes.

[q] What is the most likely diagnosis?

2 years old child presenting with fever, vesiculoulcerative lesions of the oral cavity and tongue, and localized lymphadenopathy?

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[f]IEhlcnBldGljIGdpbmdpdm9zdG9tYXRpdGlzIGR1ZSB0byBwcmltYXJ5IGluZmVjdGlvbiB3aXRoIEhTVi0xLg==

Cg==

Cg==

JiM4MjExOyBMYXRlbnQgaW4gdHJpZ2VtaW5hbCBnYW5nbGlvbi4=[Qq]

[q] What is the most likely diagnosis?

19 years old patient presenting with perioral blisters that commonly appear after stressful situations + Tzank smear shows intranuclear inclusions and multinucleated giant cells ?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IENvbGQgc29yZXMuIFJlYWN0aXZhdGlvbiBvZiBhIGxhdGVudCBIU1YtMSBpbmZlY3Rpb24gaW4gdGhlIHRyaWdlbWluYWwgZ2FuZ2xpYS4=

Cg==

Cg==[Qq]

[q] What is the most likely diagnosis?

40 years old patient presenting with acute onset of headache, fever, mental status changes (lethargy, disorientation), cranial nerve deficits, aphasia and personality changes + MRI shows edema and hemorrhagic necrosis of the temporal lobe?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFRlbXBvcmFsIGxvYmUgZW5jZXBoYWxpdGlzIGR1ZSB0byBpbmZlY3Rpb24gd2l0aCBIZXJwZXMgc2ltcGxleCB2aXJ1cyB0eXBlIDEgKEhTVi0xKS4=

Cg==

Cg==[Qq]

[q] What is the most likely diagnosis?

25 years old patient presenting with recurrent, painful genital rash + Tzank smear shows intranuclear inclusions and multinucleated giant cells ?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEhlcnBlcyBnZW5pdGFsaXMgZHVlIHRvIGluZmVjdGlvbiB3aXRoIEhTVi0yIGluZmVjdGlvbi4=[Qq]

[q] What is the most likely diagnosis?

5 years old child presenting with fever, malaise, pharyngitis, and a generalized vesicular and pruritic rash. The skin lesions appear as successive crops + Tzank smear shows intranuclear inclusions and multinucleated giant cells ?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IENoaWNrZW5wb3gu[Qq]

[q] What is the most likely diagnosis?

26 years old female presenting with unilateral painful, vesicular rash localized on a single dermatome + varicella lgG antibodies?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEhlcnBlcyBab3N0ZXIgKHNoaW5nbGVzKS4=

Cg==

Cg==[Qq]

[q] Epstein-Barr Virus establish latency in ………?

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[f]IA==Qg==IGx5bXBob2N5dGVzIChFQg==Viku

[Qq]

[q] What is the most likely diagnosis?

21 years old male presenting with fever, pharyngitis, lymphadenopathy, hepatosplenomegaly, atypical lymphocytosis, and a positive Monospot test (positive heterophile antibodies)?

 

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEhldGVyb3BoaWxlLXBvc2l0aXZlIGluZmVjdGlvdXMgbW9ub251Y2xlb3NpcyAoZ2xhbmR1bGFyIGZldmVyKSBkdWUgdG8gaW5mZWN0aW9uIHdpdGggRXBzdGVpbi1CYXJyIHZpcnVzIChFQlYpLg==[Qq]

[q] Epstein-Barr virus (EBV) commonly infects B cells, stimulating them to enter the cell cycle and proliferate continuously (a process termed “transformation” or “immortalization”) which increase the risk of …………. AIDS patients.

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[f]IEhvZGdraW4gYW5kIG5vbi1Ib2Rna2luJiM4MjE3O3MgbHltcGhvbWFzLCBpbmNsdWRpbmcgdGhlIGFnZ3Jlc3NpdmUgZGlmZnVzZSBsYXJnZSBCLWNlbGwgbHltcGhvbWFzIGFuZCBCdXJraXR0JiM4MjE3O3MgbHltcGhvbWEu[Qq]

[q] What is the most likely diagnosis?

HIV positive patient with CD4 count less than 400 presenting with white patches or plaques on the lateral border of the tongue, these lesions cannot be easily removed with scraping?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEhhaXJ5IG9yYWwgbGV1a29wbGFraWEu[Qq]

[q] Cytomegalovirus establish latency in ………?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IA==bQ==b25vbnVjbGVhciBjZWxscyAoQw==TQ==Viku

[Qq]

[q] What is the most likely diagnosis?

21 years old male presenting with fever, pharyngitis, lymphadenopathy, hepatosplenomegaly, atypical lymphocytosis, and a negative Monospot test (positive heterophile antibodies)?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEhldGVyb3BoaWxlLW5lZ2F0aXZlIG1vbm9udWNsZW9zaXMgZHVlIHRvIGluZmVjdGlvbiB3aXRoIEN5dG9tZWdhbG92aXJ1cy4=[Qq]

[q] What is the most likely diagnosis?

HIV positive patient with CD4 count less than 200 presenting with interstitial pneumonia + lung biopsy shows intranuclear inclusion bodies that have characteristic “Owl-eye” inclusion?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEludGVyc3RpdGlhbCBwbmV1bW9uaXRpcyBkdWUgdG8gQ01WIGluZmVjdGlvbi4=[Qq]

[q] What is the most likely diagnosis?

1 years old child presenting with Febrile seizures followed by erythematous maculopapular rash?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFJvc2VvbGEgaW5mYW50dW0gZHVlIHRvIGluZmVjdGlvbiB3aXRoIEh1bWFuIGhlcnBlc3ZpcnVzZXMgNi4=[Qq]

[q] What is the most likely diagnosis?

HIV positive patient with CD4 count less than 200 presenting with red purple skin lesion + Biopsy with lymphocytic inflammation?

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[f]IEthcG9zaSBzYXJjb21hLg==[Qq]

[q] ……….. replicates in dermis and cause single or multiple (<20) Flesh-colored papule with central umbilication.

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[f]IE1vbGx1c2N1bSBjb250YWdpb3N1bS4=[Qq]

[q] RNA viruses are ssRNA (like our mRNA), except ……..?

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[f]IOKAnA==cmU=cGVhdA==bw==LXZpcnVz4oCdICg=[Qq]reovirus) is dsRNA.

[q] RNA viruses are enveloped except for ………..?

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[f]IA==Yw==YWxpY2l2aXJ1c2VzLCA=[Qq]picornaviruses, reoviruses, and hepeviruses (CPR, and hepevirus).

[q] RNA viruses have helical capsids except for ………?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IA==Yw==YWxpY2l2aXJ1c2VzLCA=[Qq]picornaviruses, reoviruses, flaviviruses, togaviruses, retroviruses and hepeviruses (CPR, FTR and hepevirus).

[q] RNA viruses replicate in the cytoplasm except for ……..?

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[f]IA==bw==cnRob215eG92aXJ1c2VzIGFuZCA=cg==ZXRyb3ZpcnVzZXMgKA==[Qq]OR have both a cytoplasmic and a nuclear phase).

[q] Segmented RNA viruses include ……..?

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[q] …….. is the most common cause of viral gastrointeritis in U.S in older children and adults in daycare centers.

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[q] ………… is the most common cause of aseptic meningitis, accounting for up to 90% of cases. Cerebrospinal fluid analysis in patients with aseptic meningitis typically shows a lymphocytic pleocytosis, modestly elevated protein level, and normal glucose level.

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[q] ………. is acute painful febrile pharyngitis, characterized by vesicles on the fauces and tongue which rapidly ulcerate without skin findings due to infection with coxsaki A virus.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

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[q] ………..  is erythematous papules on the palms and soles with vesicles and ulcers in oral mucosa and around the mouth due to infection with coxsaki A virus.

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[f]IEhhbmQsIGZvb3QsIGFuZCBtb3V0aCBkaXNlYXNlLg==[Qq]

[q] Myocarditis and pericarditis can be caused by which type of  coxsaki virus?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IGNveHNha2kgQiB2aXJ1cy4=[Qq]

[q] Which type of polio vaccine?

live attenuated vaccine, taken orally, give local and systemic immunity, contraindicated in pregnancy and immunocompromised,  and Lose its potency due to improper storage (properly stored at 4° C)?

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[f]IFNhYmluIHZhY2NpbmUgb3JhbCBwb2xpbyB2YWNjaW5lIChPUFYpLg==[Qq]

[q] Which type of polio vaccine?

Formalin inactivated (killed) vaccine, taken intramuscularly, give systemic immunity only, no contraindication in pregnancy and immunocompromised, and may cause minor allergic reaction?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFNhbGsgdmFjY2luZSBpbmFjdGl2YXRlZCBwb2xpbyB2YWNjaW5lIChJUFYpLg==[Qq]

[x][restart]

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