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[h] Microbiology & Antimicrobials Flashcards

[i] Master this session in just 5 minutes.

[q] ……… is gram-negative, kidney bean-shaped diplococcic, maltose fermenter, can be cultured on Thayer-Martin VCN (vancomycin/colistin/nystatin) selective medium.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IE5laXNzZXJpYSBtZW5pbmdpdGlkaXMu

[q] What is the most likely diagnosis?

34 years old patient presenting with severe headache, projectile vomiting, and stiff neck, and nuchal rigidity + CSF Findings include elevated WBC’s (neutrophils predominant), elevated proteins, low glucose + CSF culture shows gram-negative, kidney bean-shaped diplococcic on Thayer-Martin VCN?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IE1lbmluZ2l0aXMgZHVlIHRvIE5laXNzZXJpYSBtZW5pbmdpdGlkaXMu[Qq]

[q] What is the most likely diagnosis?

34 years old patient presenting with spiking fevers, chills, arthralgias, and myalgias, as well as purpuric cutaneous lesions and hypotension + Blood culture shows gram-negative, kidney bean-shaped diplococcic on Thayer-Martin VCN?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IE1lbmluZ29jb2NjZW1pYS4=[Qq]

[q] Waterhouse-Friderichsen syndrome is a complication of meningococcemia that may involve bilateral hemorrhagic destruction of ………, disseminated intravascular coagulation (DIC), and shock.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IGFkcmVuYWwgZ2xhbmQu[Qq]

[q] ………. is gram-negative, kidney bean-shaped diplococcic, maltose nonfermenter, can be cultured on Thayer-Martin VCN (vancomycin/colistin/nystatin) selective medium.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IE5laXNzZXJpYSBnb25vcnJob2VhZS4=

[q] What is the most likely diagnosis?

27 years old male patient presenting with dysuria, frequency, urgency with purulent urethral discharge after having unprotected sexual intercourse + Gram stain of urethral discharge from affected patients shows Gram negative diplococci within leukocytes?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEdvbm9ycmhlYS4=[Qq]

[q] What is the most likely diagnosis?

27 years old male patient presenting with Mucopurulent cervicitis with cervical motion tenderness + Gram stain of cervical discharge from affected patients shows Gram negative diplococci within leukocytes?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFBlbHZpYyBpbmZsYW1tYXRvcnkgZGlzZWFzZSAoUElEKS4=[Qq]

[q] Treatment of gonococcal PID must also always include treatment for ………..?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEMuIHRyYWNob21hdGlzLiBBIHRoaXJkLWdlbmVyYXRpb24gY2VwaGFsb3Nwb3JpbiB3aWxsIHRyZWF0IHRoZSBnb25vY29jY2FsIGluZmVjdGlvbiwgYW5kIGZ1cnRoZXIgdHJlYXRtZW50IHdpdGggYXppdGhyb215Y2luIG9yIGRveHljeWNsaW5lIGlzIHJlcXVpcmVkIHRvIHRyZWF0IHRoZSBDaGxhbXlkaWEsIHdoaWNoIGlzIG5vdCBzZW5zaXRpdmUgdG8gdGhlIGJldGEtbGFjdGFtcy4=[Qq]

[q] What is the most likely diagnosis?

22 years old male patient presenting with painful, swollen, erythematous knee joint after having unprotected sexual intercourse + synovial fluid sample is purulent with large number of Wbc’s and culture shows gram-negative, kidney bean-shaped diplococcic, maltose nonfermenter on Thayer-Martin VCN (vancomycin/colistin/nystatin) selective medium?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFNlcHRpYyBhcnRocml0aXMu[Qq]

[q] …….. is the reason why development of an effective vaccine directed against the gonococcal pilus is so challenging.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEFudGlnZW5pYyB2YXJpYXRpb24u

QW50aWdlbmljIHZhcmlhdGlvbiBpcyBhIHByb2Nlc3MgYnkgd2hpY2ggdGhlIHN0cnVjdHVyYWwgZ2VuZXMgZm9yIHBpbHVzIHByb3RlaW5zIHVuZGVyZ28gcmVjb21iaW5hdGlvbiB3aXRoIGVhY2ggb3RoZXIgdG8gcHJvZHVjZSBuZXcgYW50aWdlbmljIHR5cGVzIG9mIHBpbGksIGFuZCB0aGUgYXJyYXkgb2YgZGlmZmVyZW50IGFudGlnZW5pYyBwaWx1cyB0eXBlcyBwcm9kdWNlZCBieSB0aGlzIG1lY2hhbmlzbSB0aGVvcmV0aWNhbGx5IG1heSBiZSBxdWl0ZSBsYXJnZS4=

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[q] What is the most likely diagnosis?

19 Years old patient presenting with Runny nose, facial pain, headache + gram staining shows Gram-negative diplococcus?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFNpbnVzaXRpcyBkdWUgdG8gTW9yYXhlbGxhIGNhdGFycmhhbGlzLg==[Qq]

[q] …….. gram-negative coccobacillary rod, blood-loving organism that requires both X factor (hematin) and V factor (NAD) to grow.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEhhZW1vcGhpbHVzIGluZmx1ZW56YWUu[Qq]

[q] Type B capsular material consists of a ribosyl and ribitol phosphate polymer called ………..?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFBvbHlyaWJpdG9sIHBob3NwaGF0ZSAoUFJQKS4=[Qq]

[q] H influenza type B used to be a major cause of severe, invasive infections including ……… , …….. and ………. However, since the advantage of the conjugate Hib vaccine, most H influenza infections are due to non-type B strains that cause noninvasive disease such as ……….., ……….., and …………..?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IGVwaWdsb3R0aXRpcywgbWVuaW5naXRpcywgYW5kIGJhY3RlcmVtaWEuIHNpbnVzaXRpcywgYnJvbmNoaXRpcywgb3RpdGlzIG1lZGlhLCBhbmQgY29uanVuY3Rpdml0aXM=[Qq]

[q] What is the most likely diagnosis?

34 years old immigrant patient presenting with severe headache, projectile vomiting, and stiff neck, and nuchal rigidity + CSF Findings include elevated WBC’s (neutrophils predominant), elevated proteins, low glucose + CSF culture shows gram-negative coccobacillary rod, blood-loving organism that requires both X factor (hematin) and V factor (NAD) to grow?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IE1lbmluZ2l0aXMgZHVlIHRvIEguIGluZmx1ZW56YSB0eXBlIGIgKEhpYiku[Qq]

[q] What is the most likely diagnosis?

14 years old immigrant patient presenting with fever, dysphagia, drooling, and inspiratory stridor + epiglottis  appears cherry red though inspection of the epiglottis + lateral neck x-ray is shown below?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEVwaWdsb3R0aXMu[Qq]

[q] The change in the vaccination schedule of Hib conjugate vaccine would most likely affect the epidemiology of ………..?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IE1lbmluZ2l0aXMu[Qq]

[q] Colonies of H. influenza will grow around the hemolytic S. aureus colonies resulting in the characteristic ……..?

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[f]ICYjODIyMDtzYXRlbGxpdGUmIzgyMjE7IHBoZW5vbWVub24u

[q] What is the most likely diagnosis?

24 Years old patient presenting with deep, painful ulcers  with ragged borders that are associated with a grey exudate and inguinal lymphadenopathy after unprotected sex + Dark field microscopy failed to show any organism?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IENoYW5jcm9pZCAoeW91ICYjODIyMDtkbyBjcnkmIzgyMjE7IHdpdGguIEggZHVjcmV5aSku[Qq]

[q] What is the most likely diagnosis?

12 years old child presenting with facial Cellulitis with characteristic mouse-like odor and lymphadenitis + wound culture shows Gram-negative coccobacillary rods?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFBhc3RldXJlbGxhIG11bHRvY2lkYSBpbmZlY3Rpb24u[Qq]

[q] What is the most likely diagnosis?

27 years old patient working in skinning rabbits presenting with fever, ulcer at bite site, and regional lymph node enlargement and necrosis + culture of the ulcer shows Gram-negative coccobacillary rods?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IHVsY2Vyb2dsYW5kdWxhciBkaXNlYXNlIGR1ZSB0byBGcmFuY2lzZWxsYSB0dWxhcmVuc2lzLg==[Qq]

[q] Pertussis toxin (PTx) has a potent adenylate cyclase activity by ADP ribosylation of ………. –> ↑ cAMP activity that reduces phagocytic activity locally and helps the organism to initiate infection.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEdpIChpbmhpYml0aW5nIG5lZ2F0aXZlIHJlZ3VsYXRvciBvZiBhZGVueWxhdGUgY3ljbGFzZSwgZGlzaW5oaWJpdGlvbiku[Qq]

[q] Adenylate cyclase toxin is Like ……………, adenylate cyclase toxin functions as a calmodulin-dependent adenylate cyclase that causes phagocyte dysfunction and edema.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEVkZW1hIGZhY3RvciBvZiBiYWNpbGx1cyBhbnRocmFjaXMu[Qq]

[q] Tracheal cytotoxin (TCT) is not a classic bacterial exotoxin, since it is not composed of protein, but is a peptidoglycan fragment that work by …………?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IGtpbGxpbmcgY2lsaWF0ZWQgcmVzcGlyYXRvcnkgZXBpdGhlbGlhbCBjZWxscy4=[Qq]

[q] What is the most likely diagnosis?

8 years old immigrant child presenting with paroxysms of intense cough followed by inspiratory gasp, and posttussive vomiting + gram staining shows Gram-negative, aerobic coccobacillus?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFdob29waW5nIGNvdWdoLg==[Qq]

[q] What is the most likely diagnosis?

25 years old farmer presenting with fever, which is usually prolonged and intermittent (in waves rising and falling pattern), chills, weakness, malaise, body aches, sweating and headache + blood culture shows Gram-negative coccobacillus?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEJydWNlbGxvc2lzICh1bmR1bGFudCBmZXZlciBvciBtYWx0YSBmZXZlciku[Qq]

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