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[h] Musculoskeletal System Flashcards

[i] Master this session in just 5 minutes.

[q] “What is the most likely diagnosis?”

55 years old female presenting with dry eyes with corneal ulceration, dry mouth, recurrent dental carries with bilateral parotid enlargement + Biopsy of the labial salivary gland show periductal lymphocytic infiltrate (focal lymphocytic sialadenitis) + Blood test shows SS-A (anti-Ro) and/or SS-B (anti-La)?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFNqb2dyZW4gc3luZHJvbWUuIENocm9uaWMgQiBjZWxsIHByb2xpZmVyYXRpb24gaW4gcGF0aWVudHMgd2l0aCBTUyBpbmNyZWFzZXMgdGhlIHJpc2sgb2YgZGV2ZWxvcGluZyBub24tSG9kZ2tpbiBseW1waG9tYS4=

[Qq]

[q] “What is the most likely diagnosis?”

55 years old female presenting with butterfly rash and joint pain + Blood test shows pancytopenia, Antinuclear antibodies (ANA), Anti-dsDNA antibodies, decreased C2 and C4 + Renal function test shows elevated BUN and creatinine

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFN5c3RlbWljIGx1cHVzIGVyeXRoZW1hdG9zdXMu

[Qq]

[q] The most common cause of death in SLE is ……?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFJlbmFsIGRpc2Vhc2Uu[Qq]

[q] “What is the most likely diagnosis?”

40 years old female presenting with recurrent spontaneous abortion (repeated second or third trimester miscarriages) along with laboratory findings of positive lupus anticoagulant?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEFudGlwaG9zcGhvbGlwaWQgc3luZHJvbWUu

[Qq]

[q] “What is the most likely diagnosis?”

12 years old chlid presenting with arthritis involving more than 2 joints + Salmon-pink macular rash + Daily spiking fevers?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFN5c3RlbWljIGp1dmVuaWxlIGlkaW9wYXRoaWMgYXJ0aHJpdGlzLg==

[Qq]

[q] “What is the most likely diagnosis?”

40 years old female can’t comb her hair or climb a stair + Blood test is positive for anti-Jo-1 antibodies + muscle biopsy shows Endomysial inflammation (CD8 T cells) with necrotic muscle fibers is seen on muscle biopsy?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFBvbHlteW9zaXRpcy4gQm90aCBkZXJtYXRvbXlvc2l0aXMgYW5kIHBvbHlteW9zaXRpcyBtYXkgb2NjdXIgYWxvbmUgb3IgYXMgYSBwYXJhbmVvcGxhc3RpYyBzeW5kcm9tZSBhc3NvY2lhdGVkIHdpdGggYW4gdW5kZXJseWluZyBhZGVub2NhcmNpbm9tYSAob3ZhcnksIGx1bmcsIHBhbmNyZWFzKS4=

[Qq]

[q] “What is the most likely diagnosis?”

40 years old female can’t comb her hair or climb a stair + Rash of the upper eyelids + Red papules on the elbows, knuckles, and knees + Blood test is positive for anti-Jo-1 antibodies + muscle biopsy shows Perimysial inflammation (CD4 T cells) with perifascicular atrophy on biopsy?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IERlcm1hdG9teW9zaXRpcy4gQm90aCBkZXJtYXRvbXlvc2l0aXMgYW5kIHBvbHlteW9zaXRpcyBtYXkgb2NjdXIgYWxvbmUgb3IgYXMgYSBwYXJhbmVvcGxhc3RpYyBzeW5kcm9tZSBhc3NvY2lhdGVkIHdpdGggYW4gdW5kZXJseWluZyBhZGVub2NhcmNpbm9tYSAob3ZhcnksIGx1bmcsIHBhbmNyZWFzKS4=

[Qq]

[q] “What is the most likely diagnosis?”

55 years old female presenting with Pain and stiffness in shoulders and hips without muscular weakness, fever + Lab Findings shows ↑ ESR, ↑ CRP, normal CK + symptoms show Rapid response to low-dose corticosteroids?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFBvbHlteWFsZ2lhIFJoZXVtYXRpY2Eu

[Qq]

[q] “What is the most likely diagnosis?”

Young aged female presenting with chronic musculoskeletal pain and tenderness with trigger points of focal tenderness at the trapezius, medial fat pad of the knee, and lateral epicondyle for > 3 months + Impaired attention and concentration + history of depression + All lab tests are normal?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEZpYnJvbXlhbGdpYS4=

[Qq]

[q] “What is the most likely diagnosis?”

40 years old female presenting with fluctuating, fatigable muscle weakness that worsens with repetitive motions of the same muscle groups and improves with rest + double vision and difficulty chewing + dysphonia + Electromyography shows decreased strength with repetitive stimulation + x-ray shows thymic hyperplasia?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IE15YXN0aGVuaWEgZ3JhdmlzLiBBdXRvYW50aWJvZGllcyBhZ2FpbnN0IHRoZSBwb3N0c3luYXB0aWMgbmljb3RpbmljIGFjZXR5bGNob2xpbmUgcmVjZXB0b3IgYXQgdGhlIG5ldXJvbXVzY3VsYXIganVuY3Rpb24gKHR5cGUgSUkgaHlwZXJzZW5zaXRpdml0eSByZWFjdGlvbikgd2l0aCBldmVudHVhbCBkZXN0cnVjdGlvbiBvZiB0aGUgcmVjZXB0b3JzLg==

[Qq]

[q] “What is the most likely diagnosis?”

40 years old female with history of Myasthenia Gravis presenting with muscle weakness and severe respiratory distress with low oxygen saturation in room air + she didn’t take her medication for one week + Improvement with Edrophonium test: Infusion of the short-acting cholinesterase inhibitor edrophonium (Tensilon test) increases neuromuscular transmission and provides temporary improvement in symptoms?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IE15YXN0aGVuaWMgY3Jpc2lzLg==

[Qq]

[q] “What is the most likely diagnosis?”

Patient with history of small cell lung cancer Proximal muscle weakness that improves with use + Anticholinesterase agents do not improve symptoms (Negative tensilon test)?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IExhbWJlcnQtRWF0b24gc3luZHJvbWUuIEFudGlib2RpZXMgYWdhaW5zdCBwcmVzeW5hcHRpYyBjYWxjaXVtIGNoYW5uZWxzIG9mIHRoZSBuZXVyb211c2N1bGFyIGp1bmN0aW9uIO+DoCBMZWFkcyB0byBpbXBhaXJlZCBhY2V0eWxjaG9saW5lIHJlbGVhc2UgKEZpcmluZyBvZiBwcmVzeW5hcHRpYyBjYWxjaXVtIGNoYW5uZWxzIGlzIHJlcXVpcmVkIGZvciBhY2V0eWxjaG9saW5lIHJlbGVhc2UpLg==

[Qq]

[q] “What is the most likely diagnosis?”

43 years old female presenting with thickening of the skin of the hands and feet, subcutaneous calcium deposits, heartburn and dysphagia + Color change of fingers from white to blue to red after exposure to cold temperature + lab test is positive for Anti-centromere antibodies?

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IENSRVNUIHN5bmRyb21lLg==[Qq]

[x][restart]

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