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[h] Reproductive System Flashcards

[i] Master this session in just 5 minutes.

[q] What is the most likely diagnosis?

14 years old male presenting with tall stature, absent facial and body hair, gynecomastia, small and firm testis, and mild mental retardation + lab findings show ↓ testosterone, ↑ estrogen, ↑ LH, ↑ FSH, ↓ inhibin B?

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[q] The extra x chromosome in Klinefelter syndrome is acquired due to …………… during gametogenesis.

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[q] ……….. is a male patient with one barr body.

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[q] What is the most likely diagnosis?

14 years old female presenting with primary amenorrhea with absent secondary sex characteristics, short stature, webbed neck, low posterior hair line, shield chest (broad chest with widely spaced nipples), shortened 4th metacarpals + lab findings show ↓ estrogen with ↑ LH, FSH.?

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[q] Patients with TS should undergo echocardiography to evaluate for ……………?

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[q] …………………. is given to girls with turner syndrome to promote normal sexual maturation and reduce the risk of osteoporosis.

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[q] ………….. is a female without barr body.

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[q] ……………. is a patient with both ovarian and testicular tissue present (ovotestis) with ambiguous external genitalia.

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[q] What is the most likely diagnosis?

16 years old female presenting with primary amenorrhea, enlarged breast with absent axillary and pubic hair, bilateral mass in labia majora + ultrasound shows absent uterus and internal female genitalia + karyotype shows 46-xy + lab findings show high testosterone, high estrogen and high LH ?

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[q] What is the most likely diagnosis?

A newborn child presenting with his mother with male internal genitalia and ambiguous external genitalia + lab findings show testosterone/estrogen levels are normal; DHT is low?

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[q] What is the most likely diagnosis?

A newborn female child presenting with her mother with ambiguous external genitalia with high androgen levels and low estrogen levels + the mother also presenting with hirsituism, acne, cliteromegally, and deepening of the voice?

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[q] ………………. is a disorder of migration of fetal gonadotropin-releasing hormone (GnRH) and olfactory neurons, resulting in hypogonadotropic hypogonadism and anosmia/hyposmia (decreased sense of smell).

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[q] ………… is a pea-sized gland that provide lubrication to the vaginal vestibule and are not palpable unless ductal blockage occurs resulting in fluid buildup and cyst formation. It may cause discomfort during sexual activity, walking, sitting, or exercise.

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[q] …………. is a Warty skin lesion of vulvar skin that occur due to HPV types 6 or 11.

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[q] …………… are pyknotic superficial or immature squamous cells with a dense, irregularly staining cytoplasm and perinuclear clearing which is a sign of infection with human papilloma virus (HPV).

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[q] What is the most likely diagnosis?

52 years old female presenting with leukoplakia with porcelain-white plaques with a red or violet border, valvular itching + Punch biopsy shows thinning of the epidermis and fibrosis (sclerosis) of the dermis?

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[q] What is the most likely diagnosis?

33 years old female presenting with leukoplakia, valvular itching + Punch biopsy shows thick, leathery vulvar skin?

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[q] HPV-related vulvar carcinoma is due to high-risk HPV ……………………?

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[q] Non-HPV related vulvar carcinoma arises, most often, from ……………?

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[q] ………………….. is a rare, slow growing, usually noninvasive intraepithelial (in the skin) adenocarcinoma of glandular tissue of the skin. Presents as erythematous, pruritic, ulcerated vulvar skin and are PAS+, keratin+, and S1OO-.

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[q] Daughters of women who used ……………. during their pregnancy are at a 40-fold increased risk of developing clear cell adenocarcinoma (CCA) of the vagina and cervix.

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[q] What is the most likely diagnosis?

4 years old female presenting with vaginal bleeding, and a grape-like mass protruding from the vagina + biopsy shows cytoplasmic cross-striations and positive immunohistochemical staining for desmin and myogenin?

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[q] The most common symptoms of vaginal cancer are ……………………?

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[q] What is the most likely diagnosis?

16 years old female presenting with primary amonhrea although fully developed secondary sexual characteristics + lower back pain, pelvic pressure, and defecatory rectal pain + Pelvic examination reveals a blue, bulging vaginal mass or membrane that swells with increased intraabdominal pressure (Valsalva)?

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[q] Treatment of imperforate hymen is with ……………….?

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