[qwiz style=”width: auto !important; min-height: auto !important; border-width: 4px !important; border-color: #0099cc !important; ” align=”center”]

[h] Gastrointestinal System Flashcards

[i] Master this session in just 5 minutes.

[q] …….. cause reversible block of histamine H2-receptors —> ↓ H secretion by parietal cells. Used for treatment of Peptic ulcer, gastritis, mild esophageal reflux. Has antiandrogenic effects and can cross blood-brain barrier

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEhpc3RhbWluZSBIMiBibG9ja2Vycy4=

Q2ltZXRpZGluZSwgcmFuaXRpZGluZSwgZmFtb3RpZGluZSwgbml6YXRpZGluZS4gVGFrZSBIMiBibG9ja2VycyBiZWZvcmUgeW91IGRpbmUu[Qq]

[q] …….. cause irreversible inhibition of H/K ATPase in stomach parietal cells. Used for treatment of – Peptic ulcer, gastritis, esophageal reflux, Zollinger-Ellison syndrome, component of therapy for H pylori, stress ulcer prophylaxis. ↑ risk of C difficile infection, pneumonia, acute interstitial nephritis.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFByb3RvbiBwdW1wIGluaGliaXRvcnMgKE9tZXByYXpvbGUsIGxhbnNvcHJhem9sZSwgZXNvbWVwcmF6b2xlLCBwYW50b3ByYXpvbGUsIGRleGxhbnNvcHJhem9sZSku[Qq]

[q] ……. is antacid that cause Constipation, Hypophosphatemia; Osteodystrophy, Proximal muscle weakness, Seizures as a side effect.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEFsdW1pbnVtIGh5ZHJveGlkZS4=[Qq]

[q] ……. is antacid that cause Hypercalcemia (milk-alkali syndrome), rebound acid ↑. Can chelate and ↓ effectiveness of other drugs (tetracycline) as a side effect.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IENhbGNpdW0gY2FyYm9uYXRlLg==[Qq]

[q] ……. is antacid that cause Diarrhea, hyporeflexia, hypotension, cardiac arrest as a side effects.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IE1hZ25lc2l1bSBoeWRyb3hpZGUu[Qq]

[q] …….. Bind to ulcer base, providing physical protection and allowing HCO3 secretion to reestablish pH gradient in the mucous layer. Can be used in quadruple therapy for H pylori gastritis.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEJpc211dGgu[Qq]

[q] ….. is a PGE1 analog, ↑ production and secretion of gastric mucous barrier, ↓ acid production. Used for Prevention of NSAID-induced peptic ulcers (NSAIDs block PGE1 production) and Maintenance of a PDA.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IE1pc29wcm9zdG9sLg==[Qq]

[q] …….. is a Long-acting somatostatin analog; inhibits secretion of various splanchnic vasodilatory hormones. Used for treatment of Acute variceal bleeds, acromegaly, VIPoma, carcinoid tumors.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IE9jdHJlb3RpZGUu[Qq]

[q] …….. is a 5-HT3 antagonist; ↓ vagal stimulation. Used for treatment of Control vomiting postoperatively and in patients undergoing cancer chemotherapy. Cause – Headache, constipation, QT interval prolongation, serotonin syndrome as side effects.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IE9uZGFuc2V0cm9uLg==

[q] …….. is a D2 receptor antagonist, ↑ resting tone, contractility, LES tone, motility. Used for treatment of Diabetic and postoperative gastroparesis, antiemetic, persistent GERD. Contraindicated in patients with small bowel obstruction or Parkinson disease (due to D2-receptor blockade).

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IE1ldG9jbG9wcmFtaWRlLg==

[q] ……. is a NK1 (neurokinin-1) receptor blocker in brain. Used as Antiemetic for chemotherapy-induced nausea and vomiting.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEFwcmVwaXRhbnQu

[q] ……. is Soluble fibers draw water into gut lumen, forming a viscous liquid that promotes peristalsis. Cause bloating as side effect.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEJ1bGstZm9ybWluZyBsYXhhdGl2ZXMgKFBzeWxsaXVtLCBtZXRoeWxjZWxsdWxvc2UpLg==[Qq]

[q] ………. are nonabsorbable or poorly absorbable substances that attract water into the intestinal lumen, thus distending the intestinal wall and increasing peristalsis. The laxative effect is usually fairly rapid. Cause Diarrhea, dehydration as side effects.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IE9zbW90aWMgbGF4YXRpdmVzIChNYWduZXNpdW0gaHlkcm94aWRlLCBtYWduZXNpdW0gY2l0cmF0ZSwgcG9seWV0aHlsZW5lIGdseWNvbCwgbGFjdHVsb3NlKS4=[Qq]

[q] …….. is laxative that work by Enteric nerve stimulation → colonic contraction. Cause Diarrhea and melanosis coli as side effects.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFN0aW11bGFudHMgKFNlbm5hKS4=[Qq]

[q] …….. is laxative that work by Promoting incorporation of water and fat into stool. Cause Diarrhea as side effect.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IEVtb2xsaWVudHMgKERvY3VzYXRlKS4=[Qq]

[q] ……… is an Agonist at μ-opioid receptors; slows gut motility with Poor CNS penetration (low addictive potential). Used for treatment of Diarrhea. Cause Constipation and nausea as side effects.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IExvcGVyYW1pZGUu[Qq]

[q] ………. is a combination of sulfapyridine (antibacterial) and 5-aminosalicylic acid (anti-inflammatory). Activated by colonic bacteria. Used for treatment of Ulcerative colitis, Crohn disease (colitis component).

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFN1bGZhc2FsYXppbmUu[Qq]

[q] ……. inhibits gastric and pancreatic lipase → ↓ breakdown and absorption of dietary fats. Used for treatment of Weight loss. Cause Abdominal pain, flatulence, bowel urgency/frequent bowel movements, steatorrhea; ↓ absorption of fat-soluble vitamins

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IE9ybGlzdGF0Lg==[Qq]

[q] ………. improve cholesterol solubility by reducing the amount of cholesterol secreted into the bile and increasing biliary bile acid concentration.

[c]IFNob3cgbWUgdG hlIGFuc3dlcg==[Qq]

[f]IFVyc29kZW94eWNob2xpYyBhY2lkLiBVc2VkIGZvciB0cmVhdG1lbnQgb2YgUHJpbWFyeSBiaWxpYXJ5IGNpcnJob3NpcywgZ2FsbHN0b25lIHByZXZlbnRpb24gb3IgZGlzc29sdXRpb24u[Qq]

[x][restart]

[/qwiz]